Semi-synthetic paclitaxel ke setlhare sa anticancer se sebelisoang haholo litsing tsa bongaka, se sebelisoang haholo kalafong ea mefuta e fapaneng ea mofetše ka lebaka la ts'ebetso ea sona e makatsang le litlamorao tse batlang li le chefo. ts'ebetso le ts'ebeliso ea bongaka easemi-synthetic paclitaxelka botlalo.
Mokhoa oa ts'ebetso
Mokhoa oa ts'ebetso oasemi-synthetic paclitaxelhaholo-holo ka ho thibela polymerization ea tubulin, ho senya marang-rang a lisele tsa microtubule, kahoo ho thibela ho ata ha lisele le ho etsa hore lisele li apoptosis. .
Liphello tsa Pharmacological
Semi-synthetic paclitaxel e bonts'itse ts'ebetso e makatsang ea anticancer litekong tsa pharmacological, 'me e na le phello e ntle ea kalafo ho mefuta e fapaneng ea mofetše joalo ka mofetše oa matsoele, mofets'e oa mahe le mofets'e oa matšoafo.
Thibelo ea ho ata ha lisele: semi-synthetic paclitaxel e ka thibela ho ata ha lisele tsa hlahala, haholo-holo bakeng sa lisele tse sethaleng sa mitotic.
Induction of apoptosis:semi-synthetic paclitaxel e ka baka apoptosis ea lisele tsa tumor ka ho laola mokhoa oa apoptosis oa lisele tsa tumor, e le ho fihlela sepheo sa kalafo ea tumor.
Ntlafatsa karabelo ea 'mele ea ho itšireletsa mafung: semi-synthetic paclitaxel e ka laola karabelo ea 'mele ea ho itšireletsa mafung ea lisele tsa tumor le ho ntlafatsa bokhoni ba 'mele ba ho thibela hlahala.
Kopo ea bongaka
Semi-synthetic paclitaxel e sebelisoa haholo kalafong ea mafu a fapaneng a mofetše, joalo ka mofetše oa matsoele, mofets'e oa mahe a bomme, mofets'e oa matšoafo joalo-joalo. Ts'ebetso ea ona ea bongaka e se e lemohuoa hohle, 'me e fetohile e' ngoe ea litlhare tsa bohlokoa kalafong ea lefu la tsoekere. Ts'ebelisong ea bongaka, semi-synthetic paclitaxel hangata e sebelisoa hammoho le lisebelisoa tse ling tsa chemotherapeutic ho ntlafatsa katleho ea kalafo.
Litla-morao tse chefo
Litla-morao tse chefo tsa semi-synthetic paclitaxel li batla li le tlase, empa li ntse li ka baka litlamorao tse ling, joalo ka anaphylaxis, khatello ea 'mele oa masapo, chefo ea pelo, joalo-joalo. ho ea ka boemo bo itseng ba mokuli le mamello ea lithethefatsi ho fokotsa tšusumetso ea litla-morao tse chefo ho mokuli.
Melemo ea ntlafatso ea kamoso
Ka tsoelo-pele e tsoelang pele ea saense le thekenoloji le ho teba ha lipatlisiso ka paclitaxel, lipatlisiso tsa nakong e tlang mabapi le semi-synthetic paclitaxel e tla ba e pharaletseng le e tebileng. ho tla etsoa lipatlisiso mabapi le mokhoa oa ho ntlafatsa phello ea phekolo ea semi-synthetic paclitaxel le ho fokotsa litla-morao tsa eona tse chefo. le eona e tla khonahala, ho fa bakuli ba mofetše likhetho tse nepahetseng le tse sebetsang tsa kalafo.
Qetello
Joalo ka setlhare sa bohlokoa sa anticancer,semi-synthetic paclitaxele na le mefuta e mengata ea lits'ebetso tsa bongaka. Phello ea eona ea bohlokoa ea phekolo le litla-morao tse batlang li le chefo e tlase li etsa hore e be e 'ngoe ea likhetho tsa bohlokoa bakeng sa kalafo ea li-cancer tse ngata. e phethahetseng, e fana ka mekhoa e betere ea kalafo le tšepo ea ho phela bakeng sa bakuli ba mofetše.
Tlhokomeliso: Melemo e ka bang teng le likopo tse hlahisitsoeng sehloohong sena li nkiloe lingoliloeng tse hatisitsoeng.
Nako ea poso: Nov-28-2023