Feme ea GMP e rekisa litaba tse phahameng le bohloeki bo phahameng 10-DAB Semi-synthetic Paclitaxel

Litaba tsa Sehlahisoa

Lebitso:10-DAT Semi-synthetic Paclitaxel

Nomoro ea CAS:33069-62-4

Foromo ea lik'hemik'hale:C47H51NO14

Litlhaloso:99%-102%

Mmala:phofo e tshweu kapa e batlile e tshweu

Mohloli:Taxus yunnanensis, Taxus chinensis

Mofuta:APIs

Liphello le melemo

1.Anticancer effect:10-DAB semi-synthetic paclitaxel e na le phello e matla ea anticancer, e ka thibelang ka katleho ho hōla le ho ata ha lisele tsa tumor le ho etsa hore tumor cell apoptosis. Ha e bapisoa le paclitaxel ea tlhaho, 10-DAB semi-synthetic paclitaxel e na le anticancer e phahameng. ts'ebetso le mefuta e mengata ea anticancer.

2.Safety:10-DAB semi-synthetic paclitaxel moralong le ts'ebetsong ea tlhahiso, e tsepamisitse maikutlo ho ntlafatsa polokeho ea sehlahisoa le mamello.Ka ho fetola le ho ntlafatsa sebopeho sa lik'hemik'hale tsa paclitaxel ea tlhaho, liketsahalo tsa litla-morao le liketso tse mpe li fokotsehile.

3.Pharmacokinetic properties:10-DAB semi-synthetic paclitaxel e na le thepa e molemo ea pharmacokinetic, e le hore e ka kenngoa hantle le ho ajoa 'meleng, kahoo e ntlafatsa phello ea phekolo.

4.Ho sebetsa:10-DAB semi-synthetic paclitaxel e ka sebelisoa ho phekola mefuta e sa tšoaneng ea kankere, ho akarelletsa le matšoafo, matsoele, mae a bomme, mala, le tse ling.Katleho ea eona le tšireletseho li 'nile tsa netefatsoa ka bongata ka bongaka.

Litšebeletso tsa Rōna

1.Lihlahisoa:Fana ka lihlahisoa tsa limela tsa boleng bo holimo, tse hloekileng haholo, lisebelisoa tse tala tsa meriana, le li-intermediate tsa meriana.

2.Litšebeletso tsa tekheniki:Li-extracts tse ikhethileng tse nang le litlhaloso tse khethehileng ho latela litlhoko tsa bareki.