Tšebeletso ea Phetisetso ea Theknoloji bakeng sa Mekhoa e Tloaelehileng ea Paclitaxel

Tlhaloso e Khutšoanyane:

Paclitaxel ke setlhare se thibelang hlahala se sebelisoang haholo.Ente ea paclitaxel e sebelisoang hona joale litsing tsa bongaka e sebelisa oli ea polyoxyethylene castor e le solubilizer, empa liketsahalo tsa litlamorao li phahame nakong ea ts'ebeliso ea bongaka, kahoo mokuli o hloka ho fumana kalafo ea antiallergic pele a tsamaisoa. E le ho felisa litlamorao tse mpe tse bakoang ke oli ea polyoxyethyl castor, ho hlola bofokoli ba litokisetso tse teng, le ho eketsa ho qhibiliha le botsitso ba paclitaxel, paclitaxel e tlamang albumin e ile ea hlaha. Ts'ebeletso ea Phetiso bakeng sa Mekhoa e Tloaelehileng ea Paclitaxel.Ho fumana lintlha tse ling, ka kopo ikopanye le Marang-rang.

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Paclitaxel

Metabolite ea tlhaho ea tlhaho e arohaneng le e hloekisitsoeng ho tloha makhapetla, makala le makhasi a gymnospermous taxus chinensis e ka khothalletsa microtubule polymerization le ho tsitsisa li-microtubules tse nang le polymerized.Lisele tse pepesehileng ho paclitaxel li tla bokella palo e kholo ea li-microtubules liseleng.Ho bokellana ha li-microtubules tsena ho kena-kenana le mesebetsi e sa tšoaneng ea lisele, haholo-holo ho emisa karohano ea lisele sethaleng sa mitotic, le ho thibela karohano e tloaelehileng ea lisele.

Hajoale, e sebelisoang haholo ka paclitaxel ke liente tsa anticancer le lisebelisoa tsa bongaka (ho kenyeletsoa li-stents le libalune).Ka tsoelo-pele e potlakileng ea theknoloji ea baeloji le thekenoloji ea bongaka, tšebeliso ea paclitaxel le eona e lula e hlahlojoa, 'me maemo a fapaneng a bakuli a boetse a ntlafatsoa ka ho tsoelang pele.Lumela hore haufinyane, e tla ba e sireletsehileng le e loketseng ho phekola lingaka le bakuli, 'me ho tla ba le mefuta e mengata ea litlhare tsa anticancer tse nang le paclitaxel tse nang le phello e matla ea anticancer.

Tsoelopele ea morero

Boithuto ba pele ho kliniki bo phethiloe mme tšebetso ea boitokiso e se e holile.