Paclitaxel,paclitaxel for injectable suspension and albumin-bound paclitaxel ke eng?Litšebeliso tsa mantlha ke life?Re tla li hlalosa ka bokhutšoanyane sehloohong sena.
Metabolite ea tlhaho ea bobeli e arohaneng le e hloekisitsoeng ho tloha makhapetla, makala le makhasi a gymnospermous taxus chinensis e ka khothalletsa polymerization ea microtubule le ho tsitsisa li-microtubules tse nang le polymerized. ka mesebetsi e fapaneng ea lisele, haholo-holo ho emisa karohano ea lisele sethaleng sa mitotic, le ho thibela karohano e tloaelehileng ea lisele.
E na le phello e ntle ea anti-tumor mme e sebelisoa ho alafa mofetše o tsoetseng pele oa matsoele, mofets'e oa matšoafo, mofetše oa mahe a bomme, mofetše oa hlooho le molala, mofets'e oa lisele tse bonolo le mofets'e oa tšilo ea lijo.
Paclitaxel(Taxol) is an anticancer API(Active Pharmaceutical Ingredient), e ke keng ea sebelisoa ke batho ka kotloloho.E hloka ho fuoa lik'hamphani tse tlase kapa lifeme tsa meriana hore e be e' ngoe ea API ea lithethefatsi tse felileng.
Hajoale, paclitaxel e sebelisoang haholo ke liente tse thibelang mofetše le lisebelisoa tsa bongaka (ho kenyeletsoa li-stents le libalune). Lumela hore haufinyane, e tla ba e sireletsehileng le e loketseng kalafo ea lingaka le bakuli, 'me ho tla ba le mefuta e mengata ea litlhare tse thibelang mofetše tse nang le paclitaxel tse nang le phello e matla ea ho thibela mofetše.
Paclitaxel bakeng sa ho Suspension Injectable:
Ente e nang le paclitaxel API.
Paclitaxel bakeng sa ente e boetse e kenyelletsa ente ea polyoxyethylene castor oli paclitaxel; ente ea Liposome paclitaxel; ente ea paclitaxel e tlameletsoeng ea albumin; Micellar paclitaxel le mefuta e meng ea litekanyetso.
E sebelisoa haholo mofetšeng oa matsoele, mofets'e oa matšoafo, mofets'e oa mahe a bomme le mafu a mang, 'me ke e' ngoe ea litlhare tse thibelang mofetše ka ho fetisisa hajoale.
Albumin Bound Paclitaxel:
Albumin bound paclitaxel injection ke tokiso e kopanyang paclitaxel le albumin.Ke ea paclitaxel bakeng sa ente 'me ke e' ngoe ea liente tsa paclitaxel tse sebelisoang ka ho fetisisa tse nang le tšireletso e phahameng.
Albumin paclitaxel, ea pele e keneng mahlong a batho ke Ente ea ABRAXANE(ABRAXANE For Injectable Suspension paclitaxel-bound particles for injectable suspension,albumin-bound) e amohetsoeng ke FDA ka 2005, e sebelisoang ho alafa mofetše oa matsoele oa metastatic. ho qhibiliha hape ho ka ba 130 nm, 'me ha e na lihlapolli tse chefo. Tšireletseho ea eona le phello ea eona ea phekolo e phahame haholo ho feta ea litokisetso tse tšoanang,' me e tumme haholo. Hape ke le leng la mabaka a ka sehloohong a lipatlisiso le ho etsisa. ea likhoebo tse kholo tsa meriana nakong e tlang.
E sebetsa haholo kalafong ea mofetše oa matsoele oa metastatic o hlolehang ho chemotherapy e kopaneng kapa mofets'e oa matsoele o khutlelang hape nakong ea likhoeli tse 6 kamora chemotherapy ea adjuvant.
Yunnan Hande Bio-Tech e ikemiselitse ho etsa lipatlisiso & nts'etsopele le tlhahiso eapaclitaxel,docetaxel,10-DAB semi-synthetic paclitaxel, lecabazitaxelHo feta moo, Hande e fana ka lits'ebeletso tsa phetisetso ea mahlale tse amanang le paclitaxel: liente tsa setso tsa paclitaxel; liente tsa paclitaxel tse tlamang albumin joalo-joalo, rea u amohela ho ikopanya le rona ho botsa! （Whatsapp/Wechat:+86 18187887160)
Nako ea poso: Feb-09-2023