Boroko ke karolo ea bohlokoa bophelong ba letsatsi le letsatsi ba motho, bo nang le tšusumetso ea bohlokoa bophelong ba motho ka mong 'meleng le kelellong, tšebetsong ea 'mele le ts'ebetso ea kelello.Melatonin, homone e hlahisoang ke tšoelesa ea pineal, e phetha karolo ea bohlokoa ho laola morethetho oa boroko le ho boloka boemo ba boroko.Sengoliloeng sena se tla hlahloba phello e laolang ea melatonin borokong ho latela pono ea lingoliloeng tsa litsebi.
Sebopeho le molao-motheo oa tlhahiso ea melatonin
Melatonin ke mofuta oa hormone ea indole e entsoeng le ho ntšoa ke tšoelesa ea pituitary ea mammalian pineal gland, e nang le morethetho o hlakileng.Sebakeng se nang le khanya e lekaneng, retina e utloa leseli 'me e thibela motsoako oa melatonin le secretion ka retina-hypothalamic-pineal axis.Sebakeng se lefifi, retina ha e utloe e le bobebe, 'me e khothalletsa ho qaptjoa le ho hlahisa melatonin ka retina-hypothalamic-pineal axis.
Tšusumetso ea melatonin boleng ba boroko
Melatonine khothalletsa boroko haholo-holo ka ho sebelisana le li-receptor tse khethehileng tsa melatonin ho laola oache ea circadian le ho thibela ho falimeha.Bosiu, tekanyo ea melatonin e ea phahama, e leng ho thusang ho fetola nako ea 'mele ea tlhaho le ho etsa hore motho a robale.Ka nako e tšoanang, melatonin e ka boela ea thusa ho boloka boroko ka ho thibela ho falimeha.Liphuputso li bontšitse hore phello ea taolo ea melatonin borokong e amana haufi-ufi le tekanyo le nako ea tsamaiso.
Boraro, mathata a melatonin le mafu a amanang le boroko
Ho senyeha ha melatonin ho ka baka mathata a ho robala le mathata a mang a amanang le boroko.Ka mohlala, mathata a ho robala a kang lefu la ho hlobaela, lefu la shift, le bothata ba ho ikamahanya le jet lag a amana le tšitiso ea morethetho oa melatonin.Ho feta moo, liphuputso tse ling li bontšitse hore tlhahiso e sa lekaneng ea melatonin le eona e ka eketsa kotsi ea lefu la Alzheimer, khatello ea maikutlo le mafu a mang.
sephetho
Karolo ea melatonin ho laolang boroko e 'nile ea ithutoa haholo maemong a mangata.Leha ho le joalo, ho sa tsotellehe karolo e tiisitsoeng ea melatonin ho laola boroko, ho ntse ho e-na le lipotso tse ngata tse lokelang ho hlahlojoa ho ea pele.Ka mohlala, mokhoa o khethehileng oa ho sebetsa ha melatonin o ntse o hloka ho tsoela pele ho ithutoa;Phello ea melatonin taolong ea boroko e kanna ea fapana ho batho ba fapaneng (joalo ka batho ba lilemo tse fapaneng, bong le mekhoa ea ho phela).Le ho hlahloba tšebelisano lipakeng tsa melatonin le lintlha tse ling tsa bophelo bo botle ba 'mele le kelello.
Ho feta moo, ke habohlokoa ho hlokomela hore le hoja tšebeliso ea melatonin ho laola boroko e bontša litebello tse tšepisang, polokeho ea eona, katleho ea eona le tšebeliso e nepahetseng e ntse e hloka bopaki bo bong ba bongaka.Ka hona, litaelo tsa lipatlisiso tsa nako e tlang li lokela ho kenyelletsa ho etsa liteko tse eketsehileng tsa bongaka ho netefatsa phello ea 'nete ea melatonin ho ntlafatsa boroko le mathata a amanang le eona.
sesupo
Bachman,JG,&Pandi-Perumal,SR(2012) .Melatonin: lits'ebetso tsa kliniki ho feta mathata a ho robala.Journal of pineal research,52(1),1-10.
Brayne,C.,&Smythe,J.(2005).Karolo ea melatonin borokong le bohlokoa ba eona ho tsa bongaka.Journal of Pineal Research,39(3),
Nako ea poso: Sep-27-2023