Paclitaxel e loantša mofetše joang?

Paclitaxel ke diterpenoid e ntšitsoeng ho Taxus genus Taxus, 'me bo-rasaense ba fumane hore e na le ts'ebetso e matla ea antitumor litekong tsa ho hlahloba.Hajoale,paclitaxele sebelisoa haholo kalafong ea mofetše oa matsoele, mofets'e oa mahe a bomme, mofets'e o seng nyane oa lisele tsa matšoafo, mofets'e, mofets'e oa 'metso, mofets'e oa mpa, hlahala ea hlooho le molala, sarcoma ea lisele tse bonolo le lihlahala tse ling tse kotsi,' me ke e 'ngoe ea tse etsahalang khafetsa. o ile a sebelisa chemotherapy nakong ea boikoetliso.Joale hantle-ntle paclitaxel e loantša mofetše joang?Ha re shebeng ka tlase.

Paclitaxel e loantša mofetše joang?Hoa tsebahala hore nakong ea karohano e tloaelehileng ea sele, sele e arotsoe likarolo tse peli.Ka mor'a hore chromosome e kopitsoe, khoele ea spindle e e hula ho tloha sebakeng sa eona sa pele ho ea mahlakoreng ka bobeli, 'me spindle e hloka depolymerization ea microtubules e le cytoskeleton ho theha, li-Chromosome li khona ho tlatsa mitosis feela ka ho fallela lipalong tse tlas'a ho hula ha spindle le khoele ea spindle, kahoo li-microtubules li bohlokoa haholo karohanong ea lisele.

Ka 1979, setsebi sa meriana Horwitz se ile sa fumana seopaclitaxele ka tlama ho tubulin le ho khothalletsa polymerization ea tubulin ho etsa li-microtubules, kahoo e thibela ho arohana ho tloaelehileng ha 'mele ea li-microtubules, ho etsa hore e se ke ea khona ho theha li-spindle le li-spindle filaments, ho etsa lisele Ho se khone ho arola ka tloaelo ho thibela ho ikatisa ka potlako ha lisele tsa kankere le ho etsa hore apoptosis e be teng. lisele tsa mofetše.Ka hona, har'a lithethefatsi tsa anticancer, paclitaxel e nkoa e le microtubule inhibitor ho mitosis.

Tlhokomeliso: Matla a ka bang teng le lits'ebetso tse hlalositsoeng sehloohong sena li nkiloe libukeng tse hatisitsoeng.

'malo o ekelitsoeng:Yunnan Hande Biotechnology Co., Ltd. esale e shebane le tlhahiso ea paclitaxel ka lilemo tse 28.Ke moetsi oa pele oa lefats'e ea ikemetseng oa sethethefatsi sa mofets'e se nkiloeng ke semela se amohetsoeng ke US FDA, European EDQM, Australian TGA, China CFDA, India, Japan le mekhatlo e meng ea taolo ea naha.khoebo.Haeba u batla ho rekaPaclitaxel API,ka kopo ikopanye le rona inthaneteng.