Litaba tsa Sehlahisoa
Lebitso:Indole-3-carbinol
Reneketso:indole-3-methane
Nomoro ea CAS:700-06-1
Foromo ea lik'hemik'hale:C9H9NO
Sebopeho sa molek'hule:
Tlhaloso:99% HPLC
Mmala:phofo e tšoeu
Phello ea Indole-3-carbinol
1. Tšebetso e khahlanong le li-hormone: Indole-3-methanol e ka ama tsela ea metabolic ea estrogen, ea eketsa mosebetsi oa estradiol 2-hydroxylase le tekanyo ea metabolism ea tsela ea catechol, kahoo e eketsa boemo ba 2-hydroxy-estrone ea lihomone.E ka boela ea fokotsa ho tsosoa ha litšoelesa tsa basali ka ho fokotsa tsela ea 16α-hydroxy-estrogen, ho sebelisa mosebetsi o khahlanong le li-hormone le ho thibela lihlahala tse itseng tse itšetlehileng ka estrogen.
2. Thibela ho tlamahane ha carcinogens ho DNA: Indole-3-methanol e ka thibela aflatoxin AFB1 ho tlamahane le DNA, ea thibela phello ea phetoho ea AFB1 linthong tse phelang, hape ea thibela ho tlamaha ha li-adducts tsa DNA tse amanang le carcinogens mosi oa sakerete.
3. Laola ts'ebetso ea enzyme ea 'mele' meleng: Indole-3-methanol e ka susumetsa ts'ebetso ea li-enzyme tsa metabolizing ea lithethefatsi Karolong ea I le Karolong ea II, ea eketsa ts'ebetso ea glutathione ka har'a lisele le litho tse lebisitsoeng, ka mokhoa o ngotsoeng e kenya tšebetsong mesebetsi ea glutathione S-transferase. (GST), epoxide hydrolase le quinone oxidoreductase NAD (P) H, le ho kenya letsoho tabeng ea ho tlosa chefo ea electrophile.E sireletsa lisele ho tsoa tšenyo ea oxidative mme e bapala karolo ea anticancer.
4. thibelong ea mofetše: oral indole-3-methanol e ka thusa ho thibela mefuta e mengata ea mofetše, ho kenyelletsa le mofetše oa matsoele, mofetše oa popelo, mofetše oa tšoelesa ea senya le mofets'e.
5. tšehetso bakeng sa ts'ebetso ea sebete: indole-3-methanol e na le phello e itseng ea tšireletso sebeteng.
Litšebeletso tsa Rōna
1.Lihlahisoa:Fana ka lihlahisoa tsa limela tsa boleng bo holimo, tse hloekileng haholo, lisebelisoa tse tala tsa meriana, le li-intermediate tsa meriana.
2.Litšebeletso tsa tekheniki:Li-extracts tse ikhethileng tse nang le litlhaloso tse khethehileng ho latela litlhoko tsa bareki.
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